Tantárgy adatlapja
The subject focuses on providing comprehensive information on basic micro- and nanotechnological methods used for creating miniaturized brain-machine interfaces. The lectures summarize the current trends and challenges of such devices by presenting the latest research results on perspective applications.
Historical overview of the evolution of micro- and nanotechnologies and their role in the BCI market
Fundamental building blocks to miniaturize biosensors 1: Photolithography
Fundamental building blocks to miniaturize biosensors 1: Thin-film deposition
Fundamental building blocks to miniaturize biosensors 3: Wet and dry etching
Material properties of today’s brain-machine interfaces and future challenges
Mechanical interactions between implantables and tissue
Technology and performance of soft, flexible implantable devices
Biocompatibility and long-term stability
Integrated electronics and brain-machine interfaces
Optoelectronics integrated implantable devices: opto- and thermogenetic approaches
Multimodal neuroimaging with transparent microengineered brain-machine interfaces
List of required and recommended publications:
Liu, S., Zhao, Y., Hao, W., Zhang, X. D., & Ming, D. (2020). Micro-and nanotechnology for neural electrode-tissue interfaces. Biosensors and Bioelectronics, 170, 112645. Won, S. M., Song, E., Zhao, J., Li, J., Rivnay, J., & Rogers, J. A. (2018). Recent advances in materials, devices, and systems for neural interfaces. Advanced Materials, 30(30), 1800534.
Zhang, D., Chen, Q., Shi, C., Chen, M., Ma, K., Wan, J., & Liu, R. (2021). Dealing with the foreign-body response to implanted biomaterials: strategies and applications of new materials. Advanced Functional Materials, 31(6), 2007226.
Goncalves, S. B., Ribeiro, J. F., Silva, A. F., Costa, R. M., & Correia, J. H. (2017). Design and
manufacturing challenges of optogenetic neural interfaces: a review. Journal of neural engineering, 14(4), 041001.
Z Fekete, Recent advances in silicon-based neural microelectrodes and microsystems, Sensors &
Actuators B: Chemical 2015 (2015) 300-315
Required professional competences:
fundamental knowledge in physics and neuroscience
