Tantárgy adatlapja
The goal of this course is to highlight recent results in systems biology-oriented applications. Local and guest lecturers will present the basic concepts and advanced research topics in key directions of systems biology. Discussed topics include:
Dynamical Systems Theory
Cell cycle modelling
DNA nanotechnology
Interaction databases
network visualization
Signalling network, multiomics
Proteomics
Metabolic networks
Metabolomes:
Chromosome segregation
Logic approaches
Agent-based modeling
Parameter Estimation
Evolutionary genomics
Origin of life
Bacterial cell biology
Autophagy
MAP kinase signaling
Computational neuroscience
Computational immunology
Mutational signatures
Circadian clock
High content microscopy
Systems Ecology
and others.
The program from last year can be found at: https://sites.google.com/view/applied-system-biology-course
List of the mostimportant 2–5 pieces of required and recommended literature:
Alon, U. (2019). An introduction to systems biology: design principlesof biological circuits. CRC press.
Ingalls, B. P. (2013). Mathematical modeling in systems biology: anintroduction. MIT press.
Klipp, E., Liebermeister, W., Wierling, C., & Kowald, A. (2016).Systems biology: a textbook. John Wiley & Sons.
Voit, E. (2017). A first course in systems biology.Garland Science.
